Bioactivity | 7-Methylsulfinylheptyl isothiocyanate is an activator for MAPK signaling pathway, which downregulates the melanogenesis related proteins and suppresses the melanin synthesis in B16-F1 cells. 7-Methylsulfinylheptyl isothiocyanate induces autophagy. 7-Methylsulfinylheptyl isothiocyanate is an inducer for phase II enzyme, which exhibits chemoprotective effect against carcinogen. 7-Methylsulfinylheptyl isothiocyanate can be used as cosmetic ingredient for skin whitening and anti-inflammation[1][2]. |
CAS | 129244-98-0 |
Formula | C9H17NOS2 |
Molar Mass | 219.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rose P, et al., 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. [2]. Kim AJ, et al., Effect of 7-Methylsulfinylheptyl Isothiocyanate on the Inhibition of Melanogenesis in B16-F1 Cells. Life (Basel). 2021 Feb 20;11(2):162. |