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7-Methylguanosine 5'-diphosphate sodium

CAS: 104809-16-7 F: C11H16N5NaO11P2 W: 479.21

7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues
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Bioactivity 7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].
Invitro 7-Methylguanosine 5'-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5'-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].
Name 7-Methylguanosine 5'-diphosphate sodium
CAS 104809-16-7
Formula C11H16N5NaO11P2
Molar Mass 479.21
Transport Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)