7-Methoxycoumarin-3-carboxylic acid_product_DataBase

Bioactivity

7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide[1].

Invitro

7-Methoxycoumarin-3-carboxylic acid (compound 5) (100 µM; 72 h) shows non-toxic for K562, Daudi, RPMI-8226, and Jurkat cells with IC50s of >100, >100, >100, >100 µM, respectively[1].

Name

7-Methoxycoumarin-3-carboxylic acid

CAS

20300-59-8

Formula

C11H8O5

Molar Mass

220.18

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Wiemer AJ, et al. Evaluation of a 7-Methoxycoumarin-3-carboxylic Acid Ester Derivative as a Fluorescent, Cell-Cleavable, Phosphonate Protecting Group. Chembiochem. 2016 Jan 1;17(1):52-5. [2]. Mohamed-Anis Alouini, et al. Interaction of fluorescently labeled triethyleneglycol and peptide derivatives with β-cyclodextrin. Chemphyschem. 2014 Feb 24;15(3):444-57.

PeptideDB

7-Methoxycoumarin-3-carboxylic acid

CAS: 20300-59-8 F: C11H8O5 W: 220.18