Bioactivity | 7-Ketocholesterol, toxic oxysterol, inhibits the rate-limiting step in bile acid biosynthesis cholesterol 7 alpha-hydroxylase, as well as strongly inhibiting HMG-CoA reductase (the rate-limiting enzyme in cholesterol biosynthesis). 7-Ketocholesterol induces cell apoptosis[1]. |
Name | 7-Ketocholesterol |
CAS | 566-28-9 |
Formula | C27H44O2 |
Molar Mass | 400.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |