Bioactivity | 7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1]. |
Name | 7-Hydroxymethyl-10,11-MDCPT |
CAS | 428816-69-7 |
Formula | C22H18N2O7 |
Molar Mass | 422.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wadkins RM, et al. Hydrophilic camptothecin analogs that form extremely stable cleavable complexes with DNA and topoisomerase I. Cancer Res. 2004 Sep 15;64(18):6679-83. |