Bioactivity | 7-Hydroxychlorpromazine hydrochloride is the active metabolite of Chlorpromazine (HY-12708). 7-Hydroxychlorpromazine hydrochloride can increase prolactin levels in rats. 7-Hydroxychlorpromazine hydrochloride can increase dopamine turnover and has a sedative effect. In addition, 7-Hydroxychlorpromazine hydrochloride can effectively inhibit amphetamine-induced stereotyped behavior in rats and is used in the study of psychosis[1][2]. |
CAS | 51938-11-5 |
Formula | C17H20Cl2N2OS |
Molar Mass | 371.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Meltzer H Y, et al. Effect of metabolites of chlorpromazine on plasma prolactin levels in male rats[J]. European Journal of Pharmacology, 1977, 41(4): 431-436. [2]. Perry T L, et al. 7-Hydroxychlorpromazine: potential toxic drug metabolite in psychiatric patients[J]. Science, 1964, 146(3640): 81-83. |