Bioactivity | 7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine[1]. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist[1][2]. |
Name | 7-Desmethyl-3-hydroxyagomelatine |
CAS | 166527-00-0 |
Formula | C14H15NO3 |
Molar Mass | 245.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analy [2]. Kennedy SH, et al. Agomelatine and its therapeutic potential in the depressed patient. Neuropsychiatr Dis Treat. 2007 Aug;3(4):423-8. |