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7-Desmethyl-3-hydroxyagomelatine

CAS: 166527-00-0 F: C14H15NO3 W: 245.27

7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity tha
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Bioactivity 7-Desmethyl-3-hydroxyagomelatine (3-Hydroxy-7-desmethyl agomelatine), a metabolite of Agomelatine, has less activity than Agomelatine[1]. Agomelatine is a melatonergic (MT1 and MT2) agonist and serotonergic (5HT2C) antagonist[1][2].
Name 7-Desmethyl-3-hydroxyagomelatine
CAS 166527-00-0
Formula C14H15NO3
Molar Mass 245.27
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Li M, et al. Development and validation a LC-MS/MS method for the simultaneous determination of agomelatine and its metabolites, 7-desmethyl-agomelatine and 3-hydroxy-agomelatine in human plasma: Application to a bioequivalence study. J Chromatogr B Analy [2]. Kennedy SH, et al. Agomelatine and its therapeutic potential in the depressed patient. Neuropsychiatr Dis Treat. 2007 Aug;3(4):423-8.