7-Chloro-4-(piperazin-1-yl)quinoline_product_DataBase

CAS: 837-52-5 F: C13H14ClN3 W: 247.72

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolo

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively[1].

Name

7-Chloro-4-(piperazin-1-yl)quinoline

CAS

837-52-5

Formula

C13H14ClN3

Molar Mass

247.72

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Aida M Abd El-Sattar El-Azzouny, et al. Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives. Drug Dev Res. 2020 Nov;81(7):786-802.

PeptideDB

7-Chloro-4-(piperazin-1-yl)quinoline

CAS: 837-52-5 F: C13H14ClN3 W: 247.72