| Bioactivity | 7-Acetyl paclitaxel is a microtubule depolymerization inhibitor which inhibits calcium-induced microtubule depolymerization. 7-Acetyl paclitaxel reduces the growth of J774.2 macrophages (IC50 ~ 60 nM) and increases the levels of nitric oxide (NO) and TNF in isolated mouse peritoneal macrophages[1]. |
| CAS | 92950-39-5 |
| Formula | C49H53NO15 |
| Molar Mass | 895.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ojima I, et al. Structure-activity relationship study of taxoids for their ability to activate murine macrophages as well as inhibit the growth of macrophage-like cells. Bioorg Med Chem. 2003 Jul 3;11(13):2867-88. |
7-Acetyl paclitaxel
CAS: 92950-39-5 F: C49H53NO15 W: 895.94
7-Acetyl paclitaxel is a microtubule depolymerization inhibitor which inhibits calcium-induced microtubule depolymerizat
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