Bioactivity | 7-51A 是一种有效的 PB2 抑制剂,经 ITC 测定的 KD 值为 1.64 nM。PB2 是流感 RNA 依赖性 RNA 聚合酶 (RdRP) 的重要亚基。 |
Name | 7-51A |
Formula | C22H25FN5O5P |
Molar Mass | 489.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Weining Sun, et al. Discovery of a potent inhibitor targeting the cap-binding domain of the PB2 subunit of influenza RNA-dependent RNA polymerase. Biochem Biophys Res Commun. 2023 Oct 20:678:97-101. |