Bioactivity | 7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases[1]. | |||||||||
Invitro | 7,8-Dihydroneopterin is a heterocyclic pteridine which produced and secreted by monocytes/macrophages upon stimulation with the cytokine interferon-y (IFN-y)[1].7,8-Dihydroneopterin (0.1, 0.5, 1, 2.5, 5 mM; 2 days and 5 days) inhibits growth of U373MG astroeytes[1] . Cell Viability Assay[1] Cell Line: | |||||||||
Name | 7,8-Dihydroneopterin | |||||||||
CAS | 1218-98-0 | |||||||||
Formula | C9H13N5O4 | |||||||||
Molar Mass | 255.23 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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