Bioactivity | 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A2 (PLA2) (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM)[1]. |
Invitro | 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) 对 βA(25-35) 刺激的反应有显著影响。7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) 减少 ROS 的形成[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid 相关抗体: |
CAS | 89560-01-0 |
Formula | C22H40O2 |
Molar Mass | 336.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jannike M Andersen, et al. Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease. Neurochem Res. 2003 Feb;28(2):319-26. |