| Bioactivity | 6bK TFA is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. 6bK TFA increases circulating insulin in high-fat-fed mice. Acute administration of 6bK TFA enhances glucose tolerance to oral glucose, notably to a greater extent in high-fat-fed mice[1]. |
| Target | IC50: 50 nM (IDE) |
| Name | 6bK TFA |
| CAS | 1774353-12-6 |
| Formula | C43H56F3N7O9 |
| Molar Mass | 871.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell Metab. 2014;20(2):201-203. |
6bK TFA
CAS: 1774353-12-6 F: C43H56F3N7O9 W: 871.94
6bK TFA is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. 6bK TFA increase
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