| Bioactivity | 6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors[1][2]. | ||||||
| CAS | 903899-13-8 | ||||||
| Formula | C5H6BNO3 | ||||||
| Molar Mass | 138.92 | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Store at room temperature 3 years
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| Reference | [1]. Hendricks RT, et al. 3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):410-4. [2]. Verheijen JC, et al. Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent. J Med Chem. 2009 Dec 24;52(24):8010-24. |
6-Hydroxypyridin-3-ylboronic acid
CAS: 903899-13-8 F: C5H6BNO3 W: 138.92
6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside
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