Bioactivity | 6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC50: 59 μM)[1]. |
Target | IC50: 59 μM (NMDAR) |
Name | 6-Hydroxykynurenic acid |
CAS | 3778-29-8 |
Formula | C10H7NO4 |
Molar Mass | 205.17 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Weber M, et al. 6-Hydroxykynurenic acid and kynurenic acid differently antagonise AMPA and NMDA receptors in hippocampal neurones. J Neurochem. 2001 May;77(4):1108-15. |