PeptideDB

6-Hydroxykynurenic acid

CAS: 3778-29-8 F: C10H7NO4 W: 205.17

6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydro
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Bioactivity 6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC50: 59 μM)[1].
Target IC50: 59 μM (NMDAR)
Name 6-Hydroxykynurenic acid
CAS 3778-29-8
Formula C10H7NO4
Molar Mass 205.17
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Weber M, et al. 6-Hydroxykynurenic acid and kynurenic acid differently antagonise AMPA and NMDA receptors in hippocampal neurones. J Neurochem. 2001 May;77(4):1108-15.