| Bioactivity | 6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons[1]. |
| Name | 6'-GNTI dihydrochloride |
| CAS | 2410327-94-3 |
| Formula | C27H31Cl2N5O3 |
| Molar Mass | 544.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Schmid CL, et al. Functional selectivity of 6'-guanidinonaltrindole (6'-GNTI) at κ-opioid receptors in striatal neurons. J Biol Chem. 2013;288(31):22387-22398. |
6'-GNTI dihydrochloride
CAS: 2410327-94-3 F: C27H31Cl2N5O3 W: 544.47
6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated s
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