| Bioactivity | 6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells[1]. |
| Invitro | 6-Formylpterin (2 mM) 在 HL-60 细胞中产生 ROS [1]。6-Formylpterin (0.5, 1, and 2 mM, 3 小时) 增加HL-60 和 Jurkat 细胞中 2O2 含量，导致细胞凋亡[1]。 0 --> 6-Formylpterin 相关抗体: Apoptosis Analysis[1] Cell Line: |
| Name | 6-Formylpterin |
| CAS | 712-30-1 |
| Formula | C7H5N5O2 |
| Molar Mass | 191.15 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
| Reference | [1]. Arai T, et al. 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation. Free Radic Biol Med. 2001 Feb 1;30(3):248-59. |
6-Formylpterin
CAS: 712-30-1 F: C7H5N5O2 W: 191.15
6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in
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