Bioactivity | 6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5[1]. |
Invitro | 6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1]. Apoptosis Analysis[1] Cell Line: |
Name | 6-Dehydrogingerdione |
CAS | 76060-35-0 |
Formula | C17H22O4 |
Molar Mass | 290.35 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |