6-Amino-8-trifluoromethylphenanthridine_product_DataBase

CAS: 651055-83-3 F: C14H9F3N2 W: 262.23

6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-13

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site.
CAS	651055-83-3
Formula	C14H9F3N2
Molar Mass	262.23
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Bach, et al. Isolation of drugs active against mammalian prions using a yeast-based screening assay. Nat. Biotechnol. 21(9), 1075-1081 (2003).

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