| Bioactivity | 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite |
| Formula | C44H49F2N4O7P |
| Molar Mass | 814.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite
CAS: F: C44H49F2N4O7P W: 814.85
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog. Purine nucleoside analogs have
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