Bioactivity | 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
Name | 5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite |
CAS | 142808-44-4 |
Formula | C46H50F2N5O8P |
Molar Mass | 869.89 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |