Bioactivity | 5α-Androstan-3β-ol (Androstan), a saturated sterol, is a CAR (constitutive androstane receptor) inverse agonist ligand. 5α-Androstan-3β-ol (Androstan) increases the AmB-channel conductance in a concentration dependent manner[1][2]. |
CAS | 1224-92-6 |
Formula | C19H32O |
Molar Mass | 276.46 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. I Tzameli, et al. T he xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol Cell Biol. 2000 May;20(9):2951-8. [2]. Olga S Ostroumova, et al. Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS One. 2012;7(1):e30261. |