| Bioactivity | 5-S-Cysteinyldopamine is a sulfur ether metabolite of dopamine that can induce neurodegeneration by inducing widespread oxidative stress and protein aggregation, characterized by protein carbonylation and glutathione depletion, and upregulating the expression of α-Syn and ERp57 proteins. 5-S-Cysteinyldopamine can be used in the study of neurodegenerative diseases, such as Parkinson's disease[1][2]. |
| CAS | 99558-89-1 |
| Formula | C11H16N2O4S |
| Molar Mass | 272.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rosengren E, et al. Detection of 5-S-cysteinyldopamine in human brain. J Neural Transm. 1985;63(3-4):247-53. [2]. Aureli C, et al. 5-S-cysteinyldopamine neurotoxicity: Influence on the expression of α-synuclein and ERp57 in cellular and animal models of Parkinson's disease. J Neurosci Res. 2014 Mar;92(3):347-58. |
5-S-Cysteinyldopamine
CAS: 99558-89-1 F: C11H16N2O4S W: 272.32
5-S-Cysteinyldopamine is a sulfur ether metabolite of dopamine that can induce neurodegeneration by inducing widespread
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