| Bioactivity | 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. |
| Invitro | 5'-Methylthioadenosine protects MTAP+ cells significantly better than MTAP− cells from 6TG (6′-thioguanine) toxicity[3]. Cell Viability Assay[3] Cell Line: |
| Name | 5'-Methylthioadenosine |
| CAS | 2457-80-9 |
| Formula | C11H15N5O3S |
| Molar Mass | 297.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
5'-Methylthioadenosine
CAS: 2457-80-9 F: C11H15N5O3S W: 297.33
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) dur
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