| Bioactivity | 5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1]. | |||||||||
| Target | IC50: 2.3 μM (5-LOX) | |||||||||
| Invitro | 5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM[1]. | |||||||||
| Name | 5-LOX-IN-1 | |||||||||
| CAS | 55040-82-9 | |||||||||
| Formula | C20H18N2O2S | |||||||||
| Molar Mass | 350.43 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50. |