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5-Hydroxyindole-3-acetic acid-d5

CAS: 81587-11-3 F: C10H4D5NO3 W: 196.21

5-Hydroxyindole-3-acetic acid-d5is the deuterium labeled5-Hydroxyindole-3-acetic acid(HY-W008253). 5-Hydroxyindole-3-ace
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity 5-Hydroxyindole-3-acetic acid-d5is the deuterium labeled5-Hydroxyindole-3-acetic acid(HY-W008253)[1]. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors[2].
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
Name 5-Hydroxyindole-3-acetic acid-d5
CAS 81587-11-3
Formula C10H4D5NO3
Molar Mass 196.21
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.