| Bioactivity | 5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. 5-HT3 antagonist 4 prevents diabetes-induced depressive phenotypes in mice[1]. |
| In Vivo | 5-HT3 拮抗剂 4 (4i)（0.5 和 1mg/kg/天，腹腔注射；持续 4 周）可改善糖尿病小鼠的糖尿病诱发的抑郁样行为和血清素缺乏[1]。 |
| Name | 5-HT3 antagonist 4 |
| CAS | 930478-88-9 |
| Formula | C16H12ClN3O |
| Molar Mass | 297.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Deepali Gupta, et al. A novel 5HT3 antagonist 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system. Behav Brain Res. 2016 Jan 15;297:41-50. |
5-HT3 antagonist 4
CAS: 930478-88-9 F: C16H12ClN3O W: 297.74
5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. 5-HT3 antagonist 4 prevents diabetes-induced depressive pheno
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