| Bioactivity | 5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. 5-HT3 antagonist 3 binds to 5-HT3 receptors in rat brain cortical membranes with Ki of 0.25 nM[1]. |
| Invitro | Serotonin (5-HT), involved in numerous physiological and pathophysiological processes, interacts with various distinct membrane receptors[1]. |
| Name | 5-HT3 antagonist 3 |
| CAS | 120635-47-4 |
| Formula | C20H21N3O |
| Molar Mass | 319.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. van Wijngaarden I, et al. Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. J Med Chem. 1993 Nov 12;36(23):3693-9. |
5-HT3 antagonist 3
CAS: 120635-47-4 F: C20H21N3O W: 319.40
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. 5-HT3 antagonist 3 binds to 5-HT3 recept
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