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5'-Guanylic acid-13C10,15N5 dilithium

CAS: 2483830-56-2 F: 13C10H12Li215N5O8P W: 389.98

5'-Guanylic acid-13C10,15N5 (5'-GMP-13C10,15N5 dilithium; 5'-guanosine monophosphate-13C10,15N5) dilithium is 13C and 15
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Bioactivity 5'-Guanylic acid-13C10,15N5 (5'-GMP-13C10,15N5 dilithium; 5'-guanosine monophosphate-13C10,15N5) dilithium is 13C and 15N-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
Invitro 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 0 --> 5'-Guanylic acid-13C10,15N5 dilithium 相关抗体:
Name 5'-Guanylic acid-13C10,15N5 dilithium
CAS 2483830-56-2
Formula 13C10H12Li215N5O8P
Molar Mass 389.98
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.