Bioactivity | 5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina[1][2]. |
Name | 5-Fluoromethylornithine dihydrochloride |
CAS | 124796-41-4 |
Formula | C6H15Cl2FN2O2 |
Molar Mass | 237.10 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Daune G, et al. 5-Fluoromethylornithine, an irreversible and specific inhibitor of L-ornithine:2-oxo-acid aminotransferase. Biochem J. 1988 Jul 15;253(2):481-8. [2]. Nakauchi T, et al. Prevention of ornithine cytotoxicity by nonpolar side chain amino acids in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2003 Nov;44(11):5023-8. |