| Bioactivity | 5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS-5 activity[1]. |
| Sequence | {5-FAM}-Thr-Glu-Gly-Glu-Ala-Arg-Gly-Ser-Val-Ile-Leu-Leu-Lys-(5-TAMRA)Lys-NH2 |
| Shortening | {5-FAM}-TEGEARGSVILLK(5-TAMRA)K-NH2 (TFA) |
| Formula | C111H148N22O30.xC2HF2O2 |
| Molar Mass | 2270.49 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao P, et al. Discovery of Isoindoline Amide Derivatives as Potent and Orally Bioavailable ADAMTS-4/5 Inhibitors for the Treatment of Osteoarthritis. ACS Pharmacol Transl Sci. 2022 Jun 22;5(7):458-467. |
5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA
CAS: F: C111H148N22O30.xC2HF2O2 W: 2270.49 (free base)
5-FAM-TEGEARGSVILLK(5-TAMRA)K-NH2 TFA is a substrate for ADAMTS-4/ADAMTS-5, and can be used to detect ADAMTS-4 or ADAMTS
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