Bioactivity | 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||
Invitro | 5-氯尿嘧啶是嘧啶核苷碱基尿嘧啶的氯化衍生物。在体内,它会转化为具有致突变性和遗传毒性的氯脱氧尿苷。1 尿嘧啶在无细胞髓过氧化物酶、过氧化物和氯化物系统中的 5 位被氯化,在该系统中形成次氯酸 2 5-氯尿嘧啶已在体外和体外用佛波醇 12-肉豆蔻酸酯 13-乙酸酯刺激的人嗜中性粒细胞中被发现从浅表感染部位分离的炎性人体渗出物。在角叉菜胶诱导的炎症大鼠模型和患者来源的人动脉粥样硬化主动脉组织中,从炎症部位分离的渗出液中 5-氯尿嘧啶的水平增加。3,4 参考资料 | ||||||||||||
Name | 5-Chlorouracil (fluorouracil impurity) | ||||||||||||
CAS | 1820-81-1 | ||||||||||||
Formula | C4H3ClN2O2 | ||||||||||||
Molar Mass | 146.53 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|