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5-Bromo-3-phenyl salicylic acid

CAS: 99514-99-5 F: C13H9BrO3 W: 293.11

5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of
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Bioactivity 5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM[1].
Target Ki: 140 nM (AKR1C1), 1.97 μM (AKR1C2), 21 μM (AKR1C3)
CAS 99514-99-5
Formula C13H9BrO3
Molar Mass 293.11
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. El-Kabbani O, et al., Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1). J Med Chem. 2009 May 28;52(10):3259-64.