Bioactivity | 5-(Nonyloxy)tryptamine oxalate, a high-affinity agonist for the 5-HTIDβ receptor, with an ED50 value of 68 nM. 5-(Nonyloxy)tryptamine oxalate, exhibits antitumor growth activity in vivo and enhances the ability of T cells to target tumor cells[1][2]. |
Target | ED50: 68 nM (5-HTIDβ). |
CAS | 157798-13-5 |
Formula | C21H32N2O5 |
Molar Mass | 392.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Glennon R A, et al. 5-(Nonyloxy) tryptamine: a novel high-affinity 5-HT1D. Beta. Serotonin receptor agonist[J]. Journal of medicinal chemistry, 1994, 37(18): 2828-2830. [2]. Stachura P, et al. Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors. Mol Cancer. 2023 Aug 15;22(1):136. doi: 10.1186/s12943-023-01833-8. PMID: 37582744; PMCID: PMC10426104. |