| Bioactivity | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis[1][2]. |
| Invitro | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide) is an effective inhibitor of HL60 leukemia cell growth and apoptosis-inducer[1].Apoptosis induced by 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl‑1 dependent[2]. |
| Name | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol |
| CAS | 86363-50-0 |
| Formula | C28H42O3 |
| Molar Mass | 426.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |