5,6-Epoxyretinoic acid_product_DataBase

CAS: 13100-69-1 F: C20H28O3 W: 316.43

all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s

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Bioactivity	all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s=77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 μM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid, which is a metabolite of vitamin A.
CAS	13100-69-1
Formula	C20H28O3
Molar Mass	316.43
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. McCormick, et al. Identification of 5,6-epoxyretinoic acid as an endogenous retinol metabolite. J. Biol. Chem. 257(4), 1730-1735 (1982).

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