Bioactivity | 5,6-DM-cBIMP, a cyclic nucleotide analog, is an agonist of PDE2 that can significantly enhance the cAMP and cGMP hydrolytic activities of PDE2[1][2. |
CAS | 142754-31-2 |
Formula | C14H17N2O6P |
Molar Mass | 340.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Nakashima K, et al. A Novel Inhibition Modality for Phosphodiesterase 2A[J]. SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2020, 25(5): 498-505. [2]. Jäger R, et al. Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5[J]. British journal of pharmacology, 2010, 161(7): 1645-1660. |