PeptideDB

5,5'-Dinitro BAPTA AM

CAS: 172646-47-8 F: C34H38N4O22 W: 854.68

5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the ro
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Bioactivity 5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
Invitro 5,5'-Dinitro BAPTA AM (50 μM; 20 min) attenuates evoked field excitatory postsynaptic potentials[1].
Name 5,5'-Dinitro BAPTA AM
CAS 172646-47-8
Formula C34H38N4O22
Molar Mass 854.68
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75(1):99-109.