Bioactivity | 5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1]. |
Invitro | 5,5'-Dinitro BAPTA AM (50 μM; 20 min) attenuates evoked field excitatory postsynaptic potentials[1]. |
Name | 5,5'-Dinitro BAPTA AM |
CAS | 172646-47-8 |
Formula | C34H38N4O22 |
Molar Mass | 854.68 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75(1):99-109. |