| Bioactivity | 4α-TPA is an inactive form of TPA, and is used as a negative control for TPA-activated events[1]. |
| Invitro | TPA (5, 50, and 100 ng/ml; 24 hours), but not 4α-TPA, induces MMP-9 enzyme activity (MMP-9 zym) and mRNA expression (MMP-9 mRNA) in U87 cells[1]. |
| Name | 4α-TPA |
| CAS | 63597-44-4 |
| Formula | C36H56O8 |
| Molar Mass | 616.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chiu WT, et al. Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. Neurobiol Dis. 2010;37(1):118-129. |