Bioactivity | 4A7C-301 is a Nurr1 agonist with robust neuroprotective effects in vitro. 4A7C-301 significantly ameliorates neuropathological abnormalities and improves motor and olfactory dysfunctions in AAV2-mediated α-synuclein-overexpressing male mouse models. 4A7C-301 can be used for the research of Parkinson’s disease[1]. |
Name | 4A7C-301 |
Formula | C27H38ClN9 |
Molar Mass | 524.10 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kim W, et al. An optimized Nurr1 agonist provides disease-modifying effects in Parkinson's disease models. Nat Commun. 2023 Jul 18;14(1):4283. |