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4-Nitroso hydrochlorothiazide-13C,15N2,d2

CAS: F: C613CH5D2ClN215N2O5S2 W: 331.73

4-Nitroso hydrochlorothiazide-13C,15N2,d2 is the deuterium, 13C-, and 15-labeled 4-Nitroso hydrochlorothiazide.
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Bioactivity 4-Nitroso hydrochlorothiazide-13C,15N2,d2 is the deuterium, 13C-, and 15-labeled 4-Nitroso hydrochlorothiazide[1].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[7].
Name 4-Nitroso hydrochlorothiazide-13C,15N2,d2
Formula C613CH5D2ClN215N2O5S2
Molar Mass 331.73
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.