| Bioactivity | 4-Nitro-3-(trifluoromethyl)phenol (TFM) is a piscicide. It is toxic to sea lamprey (P. marinus) with LC50 values ranging from 1.97 to 2.11 and 2.05 to 2.21 mg/L for sac and swim-up fry, respectively, 1.6 to 2.45 mg/L for juveniles, and 1.6 to 1.63 mg/L for adults. It is also toxic to juvenile lake sturgeon (A. fulvescens) less than 100 mm in size but not to a variety of other fish species. 4-Nitro-3-(trifluoromethyl)phenol (TFM) (50 μM) uncouples oxidative phosphorylation by 22 and 28% in isolated sea lamprey and rainbow trout (O. mykiss) liver, respectively. 4-Nitro-3-(trifluoromethyl)phenol (TFM) has been used as lampricides in the control of larval sea lamprey populations. |
| CAS | 88-30-2 |
| Formula | C7H4F3NO3 |
| Molar Mass | 207.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Boogaard, et al. Acute toxicity of TFM and a TFM/niclosamide mixture to selected species of fish, including lake sturgeon (Acipenser fulvescens) and mudpuppies (Necturus maculosus), in laboratory and field exposures. J. Great Lakes Res. 29(Suppl 1), 529-541 (2003). |
4-Nitro-3-(trifluoromethyl)phenol
CAS: 88-30-2 F: C7H4F3NO3 W: 207.11
4-Nitro-3-(trifluoromethyl)phenol (TFM) is a piscicide. It is toxic to sea lamprey (P. marinus) with LC50 values ranging
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