| Bioactivity | 4'-Methoxy-S-trityl-L-cysteinol is an allosteric inhibitor of vertebrate Kinesin Spindle Protein (KSP). 4'-Methoxy-S-trityl-L-cysteinol significantly enhances its inhibitory activity against NCI60 tumor cells by modifying the trityl and cysteine groups. Its EC50 for bipolar spindle formation is 28 μM, showing stronger inhibitory potency than the parent molecule and monastrol. |
| CAS | 1338701-15-7 |
| Formula | C23H25NO2S |
| Molar Mass | 379.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Synthesis and characterization of tritylthioethanamine derivatives with potent KSP inhibitory activity |
4'-Methoxy-S-trityl-L-cysteinol
CAS: 1338701-15-7 F: C23H25NO2S W: 379.52
4'-Methoxy-S-trityl-L-cysteinol is an allosteric inhibitor of vertebrate Kinesin Spindle Protein (KSP). 4'-Methoxy-S-tri
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