| Bioactivity | 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory drug (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS)[1]. |
| Invitro | 4-hydroxyphenylbutazone is isolated from incubations of phenylbutazone with either ram seminal vesicle microsomes or horseradish peroxidase. 4-hydroxyphenylbutazone is ineffective inhibitor of PHS cyclooxygenase[1]. |
| Name | 4-Hydroxyphenylbutazone |
| CAS | 16860-43-8 |
| Formula | C19H20N2O3 |
| Molar Mass | 324.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hughes MF, et, al. Prostaglandin hydroperoxidase-dependent oxidation of phenylbutazone: relationship to inhibition of prostaglandin cyclooxygenase. Mol Pharmacol. 1988 Aug;34(2):186-93. |
4-Hydroxyphenylbutazone
CAS: 16860-43-8 F: C19H20N2O3 W: 324.37
4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory drug (NSAID)
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