| Bioactivity | 4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1]. | ||||||||||||
| Invitro | 4-Hydroxyphenyl acetate (5 μM; 24 h) protects retinal pigment epithelial (RPE) cells from oxidative stress-induced cell death[1].4-Hydroxyphenyl acetate (5 μM; 24 h; ARPE-19 cells) inhibits the increase of ROS in response to oxidative stress and up-regulated the expression of cytoprotective genes including NQO1 and HO-1 genes[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | 4-Hydroxyphenyl acetate | ||||||||||||
| CAS | 3233-32-7 | ||||||||||||
| Formula | C8H8O3 | ||||||||||||
| Molar Mass | 152.15 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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4-Hydroxyphenyl acetate
CAS: 3233-32-7 F: C8H8O3 W: 152.15
4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hy
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