Bioactivity | 4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM[1][2]. | |||||||||
Name | 4-Hydroxyestradiol | |||||||||
CAS | 5976-61-4 | |||||||||
Formula | C18H24O3 | |||||||||
Molar Mass | 288.38 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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