Bioactivity | 4-Cyano-3-methylisoquinoline is an inhibitor for protein kinase A (PKA) with an IC50 of micromolar level. 4-Cyano-3-methylisoquinoline reverses morphine tolerance in mouse model[1]. |
CAS | 161468-32-2 |
Formula | C11H8N2 |
Molar Mass | 168.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Smith FL, et al., The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Res. 2003 Sep 19;985(1):78-88. |