| Bioactivity | 4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL. | ||||||||||||
| Target | IC50: 1.89 mM (monophenolase), 1.10 mM (diphenolase) | ||||||||||||
| Invitro | 4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1]. | ||||||||||||
| Name | 4-Chlorosalicylic acid | ||||||||||||
| CAS | 5106-98-9 | ||||||||||||
| Formula | C7H5ClO3 | ||||||||||||
| Molar Mass | 172.56 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008 |
4-Chlorosalicylic acid
CAS: 5106-98-9 F: C7H5ClO3 W: 172.56
4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1
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