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4-Bromo-3-hydroxybenzoic acid

CAS: 14348-38-0 F: C7H5BrO3 W: 217.02

4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of
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Bioactivity 4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes[1][2].
Invitro IC50: 1 mM (Rat fetal histidine decarboxylase (HDC)), 1 mM (Ratgastric HDC), 1 mM (Hog kidney aromatic-L-amino acid decarboxylase), 1 mM (Rat gastric mucosa aromatic-L-amino acid decarboxylase)[1]
Name 4-Bromo-3-hydroxybenzoic acid
CAS 14348-38-0
Formula C7H5BrO3
Molar Mass 217.02
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month