| Bioactivity | 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane. | ||||||||||||
| Name | 4-Aminopyridine | ||||||||||||
| CAS | 504-24-5 | ||||||||||||
| Formula | C5H6N2 | ||||||||||||
| Molar Mass | 94.11 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. Nature, 1980. 283(5747): p. 570-2. [2]. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76. |